Mesopotamia is a region in the northeast of Argentina bordered to the north by Paraguay, to the east by Brazil and Uruguay, to the south and west by the Pampas region, and in the northwest by the Chaco region.
The following provinces are considered part of Mesopotamia:
Frequent connections between Posadas, Corrientes, Rosario and Buenos Aires.
- The main highlight of this area is the Iguazú Falls in Misiones.
- The ruins of Jesuit missions in San Ignacio Miní, on the road between Posadas and Puerto Iguazú.
- The extensive wetlands of the Esteros del Iberá, in Corrientes province. Similar to the more well-known Pantanal in Brazil. The main centre for visiting this area is the town of Colonia Carlos Pellegrini.