Middle Florida is a region in the Florida Panhandle between the Apalachicola and Suwannee Rivers. It includes the six easternmost counties of the Panhandle (Franklin, Gadsden, Jefferson, Leon, Liberty, and Wakulla).
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1 Tallahassee International Airport (TLH IATA) is in the region. Important airports in (relatively) nearby regions include Orlando International Airport (MCO IATA) in Orlando, Central Florida and Hartsfield–Jackson Atlanta International Airport (ATL IATA) in Georgia.